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DOC, Doc, doc or DoC may refer to:

People and characters

The D.O.C., American rapper (born 1968)
Doc Gallows (born 1983), ring name of American professional wrestler Drew Hankinson
Doc Redman (born 1997), American professional golfer

Doc Adams (Gunsmoke), in the TV series Gunsmoke
Doc Analyn, in the Philippine TV series Abot-Kamay na Pangarap
Doc Boy, from the Garfield series
Emmett Brown, a scientist from Back to the Future
Doc Daneeka, in the novel Catch-22
Medical Officer Frank "Doc" DuFresne, in the web series Red vs. Blue
Doc Hudson, in the film Cars
Doc Louis, in the video game series Punch-Out!!
Doc McStuffins, a Disney Junior title character
Monte 'Doc' Parker, in the series Third Watch
Doc Saturday, in the series The Secret Saturdays
Doc Savage, a pulp fiction hero
Danny Torrance, a.k.a. Doc, in Stephen King's novel The Shining, its adaptations and as the protagonist in the sequel novel Doctor Sleep
Doc (Buffyverse), in Buffy the Vampire Slayer
Doc (Chrono Cross)
Doc (G.I. Joe), two characters in the G.I. Joe universe
Doc (cartoon character), an animated cat introduced by Walter Lantz Studios in 1959
Doc, in the series Fraggle Rock
Doc, in the 2013 animated film Escape from Planet Earth
Doc, a short-eared, long-legged dog, in the cartoons of Elmer Andrews Bushnell
Doc, a dwarf in the animated 1937 Disney film Snow White and the Seven Dwarfs
Doc, shopkeeper in Everybody Hates Chris

Dóc, a village in Csongrád County, Hungary
Dóc, the Hungarian name for Dolaţ village, Livezile, Timiș, Romania
DOC, the National Rail station code for Dockyard railway station, Plymouth, England
DOC, the 3-letter ISO alpha-3 code for the Democratic Republic of Congo

Doc (1975 TV series), a 1975–1976 American sitcom
Doc (2001 TV series), a 2001–2004 American medical drama
Doc (2025 TV series), a 2025 American medical drama based on the Italian TV series of the same name
Doc – Nelle tue mani, a 2020 Italian medical drama TV series, known simply as Doc in translation
"D.O.C." (Lost), a 2007 television episode

Doc+, a Russian medical company
Dartmouth Outing Club, the oldest and largest collegiate outing club in the United States
Documentary Organization of Canada, known as DOC, a non-profit organization supporting documentary filmmakers in Canada
Doc Films, a University of Chicago film society
Christian Church (Disciples of Christ), a religious denomination in the United States often referred to by the acronym "D.O.C."

United States Department of Commerce, the Cabinet department of the United States government concerned with promoting economic growth
New Zealand Department of Conservation, the public service department of New Zealand charged with the conservation of New Zealand's natural and historical heritage
Department of Corrections, an umbrella term referring to a governmental agency responsible for overseeing the incarceration of persons convicted of crimes within a particular jurisdiction

Doc (computing) (.doc), a word processing file format, typically used by Microsoft Word
DiskOnChip, a type of flash memory device
Dave's own version of Citadel, a bulletin board software variant
Department of Computing, Imperial College London, the computer science department at Imperial College London

Day-old cockerel, a term in falconry
Diesel Oxidation Catalyst, a diesel retrofit system for automobiles
Dissolved organic carbon, a molecule classification
Documentation (abbreviated: doc, docs), a set of documents provided on paper, or online, or on digital or analog media, such as audio tape or CDs
Doc (aircraft), one of two airworthy Boeing B-29 Superfortress heavy bombers
ISO 639-3 code for the North Dong, language or dialect of China
Declaration of conformity, a document declaring that a specific product complies with all relevant legal requirements